REBECCA Gibney is to appear alongside former West Wing star Rob Lowe in the $25 million, four-hour US mini-series Salem's Lot.

The remake of Stephen King's horror hit will be filmed next month in Melbourne, with Lowe starring as writer Ben Mears, who returns to his New England home town to discover it has been infiltrated by a vampire.

The Nine Network has first option on Australian rights to the mini-series, which is being produced by Warner Bros for the US cable network TNT.

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